First try to turn off and disable your Windows and any other Anti-virus program Firewall. Also List your PC specifications. Have you tried reinstalling the Game ?
If you want to play RUSE online, then the following Internet Ports are Required. read this:
Also go through this information:
Are you getting any 'Could not Communicate with Account Server' Message ?
Find “HOSTS.txt” file under
Open it with notepad, and ‘Delete’ everything below these two lines of text:
Now save the file, do make a Backup of this file, reboot, and run the game launcher/game executable as an administrator.
I would also suggest to empty the DNS cache for those who still got the problem. It can be simply done by entering
into the windows shell. (Run -> type: cmd, and then press Enter).
There is an ongoing similar Topic about this issue: