I know Assassin's Creed 3 is just in the pipelines and nothing has been announced aside from the Brotherhood expansion coming late 2010, but i was on the Assassin's Creed wiki, reading up on the Altair Armour and the following bit got me thinking:
"In any case, the armors location during Desmond's time is not clear. But given the armor's unbreakable nature, if Desmond is ever able to find this armor set; he will be able to use it as bullet-proof armor."
So at a rough guess, Ezio is buried in it, so it got me thinking the bullet proof armour would be a must have in Desmond's 2012 quest, so he would probably collect seals or bits of map which after so many pieces would locate the casket of Ezio (assuming The order of assassin's moved the Casket to the states some period following the events of Ezio's adventures) and after opening the casket wears Altair's Armour.
I know, to much time on my hands