Okay basically, I had las vegas installed before, This is the first game btw, Not vegas 2. So i wanted to play again so i installed it downloaded some patches, But once i tried to launch the game it never launched, it just done the loading disk sign that it does and thats all but it was working before that.
I would suggest doing a complete uninstall, then check to make sure that the program folder is gone from the C:\Program Files\Ubisoft path, and also delete the ...My Documents\Ubisoft\R6Vegas folder as well.
Then start with installing just the game and try to play it without applying any patch. If it works, then fine find the latest OFFICIAL patch and try it.
If it doesn't work from scratch on a fresh install then there is something with your system that had to have changed since the first time it did work for you.